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Anti-GSK3B Phospho Antibody EPR2286Y
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Also for GSK3B (NM_002093)
|A phospho-specific peptide corresponding to residues surrounding Serine 9 of human GSK3 beta was used as an immunogen. The antibody only detects GSK3 beta phosphorylated on Serine 9.|
||WB: 1:10,000 -20,000; IHC: 1:100 -250; ICC: 1:100 -250
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens glycogen synthase kinase 3 beta (GSK3B), transcript variant 1|
|GSK3beta isoform; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta|
|Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]. |
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Wnt Signaling Pathway
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Western blot analysis on 293T cell lysates using anti-Phospho-GSK3 beta (pS9) RabMAb (TA303847), 1:20,000 dilution. Cells were either (A) untreated (B) treated with Calyculin A.
Immunohistochemical analysis of paraffin-embedded human ovarian carcinoma using Phospho-specific anti-GSK3 beta (pS9) RabMAb (TA303847).