Home Antibody All anti-GRTP1 antibodies
Also for GRTP1 (NM_024719)
|GRTP1 antibody was raised against a 16 amino acid peptide from near the center of human GRTP1.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens growth hormone regulated TBC protein 1 (GRTP1), transcript variant 1|
|Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver (1). GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.|
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Western blot analysis of GRTP1 in SK-N-SH cell lysate with GRTP1 antibody at 1 µg/ml in the (A) absence and (B) presence of blocking peptide.