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Anti-GRIA1 Antibody E308
Also for GRIA1 (NM_000827)
|A synthetic peptide corresponding to residues near N-terminus of human Glutamate receptor 1 was used as immunogen. Predicted to cross-react with rat, based on sequence homology.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1: 1000; IHC: 1:50; IP: 1:30
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Mouse, Rat
|Homo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 1|
|GluA1; GLUH1; GLUR1; GLURA; HBGR1|
|Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).|
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Western blot - Glutamate Receptor 1 (AMPA subtype) antibody [E308]; Anti-Glutamate Receptor 1 (AMPA subtype) antibody [E308] at 1/1000 dilution + SH-SY5Y cell lysate.Predicted band size : 101 kDa.Observed band size : 106 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Glutamate Receptor 1 (AMPA subtype) antibody [E308]; Ab32436, at a 1/50 dilution, staining Glutamate Receptor 1 (AMPA subtype) in paraffin embedded human brain tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glutamate Receptor 1 (AMPA subtype) antibody [E308]; Immunohistochemical analysis of Human hippocampus tissue, staining Glutamate Receptor 1 (AMPA subtype) with ab32436. Antigen retrieval was performed by heat mediation in a citrate buffer (pH 6). Samples were blocked with 10% normal goat serum for 30 minutes before incubating with primary antibody (1/20) for 2 hours. A biotinylated anti-rabbit IgG was used as the secondary antibody and staining was detected using DAB.