Home Antibody All anti-GRAP antibodies
Also for GRAP (NM_006613)
|Synthetic peptide corresponding to a region within amino acids 155 and 217 of GRAP (Uniprot ID#Q13588)|
|Human (Predicted: Mouse, Rat, Rhesus Monkey, Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (92%)
|Homo sapiens GRB2-related adaptor protein (GRAP)|
Entrez Gene 10750 Human
Entrez Gene 71520 Mouse
Entrez Gene 363616 Rat
Entrez Gene 702473 Monkey
|This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. [provided by RefSeq]|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Sample (30 ug of whole cell lysate). A: A549 12% SDS PAGE. TA308618 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded U373 xenograft, using GRAP(TA308618) antibody at 1:100 dilution.
Immunofluorescence analysis of methanol-fixed A549, using GRAP(TA308618) antibody at 1:500 dilution.