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Home Antibody All anti-GPX1 antibodies

Anti-GPX1 Antibody EPR3311

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307688
  • Rabbit monoclonal antibody against GPX1(clone EPR3311)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424631) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GPX1 was used as an immunogen.
Clone NameEPR3311 IsotypeTissue culture supernatant
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens glutathione peroxidase 1 (GPX1), transcript variant 1
Alternative NameGPXD; GSHPX1
Database LinkNP_000572
Entrez Gene 2876 Human
Entrez Gene 24404 Rat
FunctionGPX1 is a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and it is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase. This active site is coded by UGA, normally functioning as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk.
Related PathwayDruggable Genome Glutathione metabolismArachidonic acid metabolismAmyotrophic lateral sclerosis (ALS)Huntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Glutathione Peroxidase 1 antibody [EPR3311]; All lanes : Anti-Glutathione Peroxidase 1 antibody [EPR3311] at 1/1000 dilution.Lane 1 : Human fetal liver lysate .Lane 2 : SH SY5Y cell lysate.Lane 3 : THP1 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 22 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Glutathione Peroxidase 1 antibody [EPR3311]; TA307688, at 1/100 dilution, staining Glutathione Peroxidase 1 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry.

 

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