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Anti-GPX1 Antibody EPR3311
Also for GPX1 (NM_000581)
|A synthetic peptide corresponding to residues in human GPX1 was used as an immunogen.|
||Tissue culture supernatant
|Rat, Human (Does not react with: Mouse)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
|Does not react with Mouse. Is unsuitable for Flow Cyt.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt.
|Homo sapiens glutathione peroxidase 1 (GPX1), transcript variant 1|
Entrez Gene 2876 Human
Entrez Gene 24404 Rat
|GPX1 is a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and it is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase. This active site is coded by UGA, normally functioning as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk.|
|Druggable Genome Glutathione metabolismArachidonic acid metabolismAmyotrophic lateral sclerosis (ALS)Huntington's disease|
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Western blot - Glutathione Peroxidase 1 antibody [EPR3311]; All lanes : Anti-Glutathione Peroxidase 1 antibody [EPR3311] at 1/1000 dilution.Lane 1 : Human fetal liver lysate .Lane 2 : SH SY5Y cell lysate.Lane 3 : THP1 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 22 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Glutathione Peroxidase 1 antibody [EPR3311]; TA307688, at 1/100 dilution, staining Glutathione Peroxidase 1 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry.