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Home Antibody All anti-GPHN antibodies

Anti-GPHN TRUEMAB Antibody Clone OTI3B6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502217 GPHN (Gephyrin) mouse monoclonal antibody, clone OTI3B6 (formerly 3B6) 100ul $379 In Stock
LC402806 GPHN HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502217 Carrier-free (BSA/glycerol-free) GPHN mouse monoclonal antibody, clone OTI3B6 (formerly 3B6) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
IHC(4)
IF(1)
FC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human GPHN (NP_065857) produced in HEK293T cell.
Clone NameClone OTI3B6 IsotypeIgG2a
Species ReactivityHuman, Monkey Concentration0.61 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Predicted MW Explanation 83.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens gephyrin (GPHN), transcript variant 1
Alternative NameGEPH; GPH; GPHRYN; HKPX1; MOCODC
Database LinkNP_065857
Entrez Gene 10243 Human
Entrez Gene 709677 Monkey
FunctionThis gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GPHN (RC205986, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GPHN.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-GPHN monoclonal antibody.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-GPHN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502217)
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Anti-GPHN mouse monoclonal antibody (TA502217) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GPHN(RC205986).
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HEK293T cells transfected with either RC205986 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-GPHN antibody(TA502217), and then analyzed by flow cytometry.
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Flow cytometric Analysis of Jurkat cells, using anti-GPHN antibody(TA502217),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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