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Home Antibody All anti-GOPC antibodies

Anti-GOPC Antibody EPR4079

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307069
  • Rabbit monoclonal antibody against GOPC(clone EPR4079)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412502) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(6)
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Also for GOPC (NM_020399)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GOPC was used as an immunogen.
Clone NameEPR4079 IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:50 - 1:100; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Rat

Reference Data

Target NameHomo sapiens golgi-associated PDZ and coiled-coil motif containing (GOPC), transcript variant 1
Alternative NameCAL; dJ94G16.2; FIG; GOPC1; PIST
Database LinkNP_065132
FunctionGOPC (Golgi-associated PDZ and coiled-coil motif-containing protein), also known as PIST, is a PDZ domain-containing Golgi protein that plays a role in intracellular protein trafficking and degradation (1, 2). GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels (1). It may also regulate intracellular trafficking of the ADR1B receptor and play a role in autophagy (1). GOPC interacts with golgin-60, a Golgi-localized protein, by colocalizing to Golgi membranes (3). Overexpression of GOPC results in CFTR intracellular retention and degradation in lysosomes (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PIST antibody [EPR4079]; All lanes : Anti-PIST antibody [EPR4079] at 1/1000 dilution.Lane 1 : A375 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : Fetal kidney lysate.Lane 4 : PC-3 cell lysate.Lane 5 : Human prostate lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 51 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PIST antibody [EPR4079]; Immunohistochemical staining of PIST expression in paraffin-embedded Human stomach tissue using TA307069 at 1/250 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PIST antibody [EPR4079](TA307069); TA307069 showing positive staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PIST antibody [EPR4079](TA307069); TA307069 showing positive staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PIST antibody [EPR4079](TA307069); TA307069 showing positive staining in Normal kidney tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PIST antibody [EPR4079](TA307069); TA307069 showing positive staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PIST antibody [EPR4079](TA307069); TA307069 showing positive staining in Normal ovary tissue.

 

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