Home Antibody All anti-GNA15 antibodies
Also for GNA15 (NM_002068)
|Synthetic peptide surrounding amino acid 356of human G 15|
|Human, mouse, rat
||WB: 0.5-4ug/ml, IHC: 5-20ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit anti-Ga15 polyclonal antibody in PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Homo sapiens guanine nucleotide binding protein (G protein), alpha 15 (Gq class) (GNA15)|
Entrez Gene 2769 Human
Entrez Gene 14676 Mouse
Entrez Gene 89788 Rat
|Ga16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-ß and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.|
|Druggable Genome Calcium signaling pathway|
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Western blot analysis of G alpha-15 expression in 3T3 cell lysate.