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Anti-GNA13 Antibody EPR5436
Also for GNA13 (NM_006572)
|A synthetic peptide corresponding to residues in human G protein alpha 13 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens guanine nucleotide binding protein (G protein), alpha 13 (GNA13), transcript variant 1|
|G protein alpha 13 belongs to the family of heterotrimeric guanine nucleotide-binding proteins that provide a link between membrane receptors and a set of signaling molecules inside the cell. The alpha-subunit of heterotrimeric G13 proteins regulates multiple cell-type dependent intracellular and cellular events (1). G protein alpha 13 activates Rho through direct stimulation of the guanine nucleotide exchange factor p115RhoGEF. Like all G-proteins, Rho cycles between the inactive GDP bound and active GTP bound form (2).|
Signaling by GPCR
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Western blot - Anti-G protein alpha 13 antibody [EPR5436]; All lanes : Anti-G protein alpha 13 antibody [EPR5436] at 1/1000 dilution.Lane 1 : Y79 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 44 kDa.
Other-Anti-G protein alpha 13 antibody [EPR5436](ab128900); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-G protein alpha 13 antibody [EPR5436]; ab128900, at a 1/250 dilution, staining G protein alpha 13 in paraffin embedded Human kidney tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-G protein alpha 13 antibody [EPR5436]; ab128900, at a 1/250 dilution, staining G protein alpha 13 in paraffin embedded Human bladder carcinoma tissue by Immunohistochemistry.