Home All anti-GNA13 antibodies
Anti-GNA13 Antibody EPR5436
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for GNA13 (NM_006572)
|A synthetic peptide corresponding to residues in human G protein alpha 13 was used as an immunogen.|
|Human, Mouse, Rat
||WB: 1:10,000 - 50,000; IHC 1:100 - 250; IP: 1:10 - 100;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens guanine nucleotide binding protein (G protein), alpha 13 (GNA13)|
|G protein alpha 13 belongs to the family of heterotrimeric guanine nucleotide-binding proteins that provide a link between membrane receptors and a set of signaling molecules inside the cell. The alpha-subunit of heterotrimeric G13 proteins regulates multiple cell-type dependent intracellular and cellular events (1). G protein alpha 13 activates Rho through direct stimulation of the guanine nucleotide exchange factor p115RhoGEF. Like all G-proteins, Rho cycles between the inactive GDP bound and active GTP bound form (2).|
Signaling by GPCR
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Western blot analysis on (A) Y79, (B) 293T, and (C) HepG2 cell lysates using anti-G protein alpha 13 RabMAb.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-G protein alpha 13 RabMAb.
Immunohistochemical analysis of paraffin-embedded human bladder carcinoma tissue using anti-G protein alpha 13 RabMAb.