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Anti-GMDS TRUEMAB Antibody Clone OTI2A1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA502141 GMDS mouse monoclonal antibody, clone OTI2A1 (formerly 2A1) 100ul 379
In Stock
LC419903 GMDS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502141 Carrier-free (BSA/glycerol-free) GMDS mouse monoclonal antibody, clone OTI2A1 (formerly 2A1) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human GMDS (NP_001491) produced in HEK293T cell.
Clone NameClone OTI2A1 IsotypeIgG2a
Species ReactivityHuman Concentration0.64 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:2000,
Predicted MW Explanation 41.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens GDP-mannose 4,6-dehydratase (GMDS), transcript variant 1
Alternative NameGMD; SDR3E1
Database LinkNP_001491
Entrez Gene 2762 Human
FunctionGDP-mannose 4,6-dehydratase (GMD; EC catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM].
Related PathwayDruggable Genome Fructose and mannose metabolismAmino sugar and nucleotide sugar metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMDS (RC200471, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GMDS.
Western blot analysis of extracts (10ug) from a mouse tissue by using anti-GMDS monoclonal antibody. (1:200)


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