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Anti-GLI1 TRUEMAB Antibody Clone OTI4B3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA803888 GLI1 mouse monoclonal antibody, clone OTI4B3 (formerly 4B3) 100ul 325
In Stock
LC417412 GLI1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF803888 Carrier-free (BSA/glycerol-free) GLI1 mouse monoclonal antibody, clone OTI4B3 (formerly 4B3) 100ug $450 3 Days
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 755-1106 of human GLI1 (NP_005260) produced in E.coli.
Clone NameClone OTI4B3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 117.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens GLI family zinc finger 1 (GLI1), transcript variant 1
Alternative NameGLI
Database LinkNP_005260
Entrez Gene 2735 Human
FunctionThis gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
Related PathwayStem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsEmbryonic stem cellsTranscription FactorsDruggable Genome Hedgehog signaling pathwayPathways in cancerBasal cell carcinoma

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GLI1 (RC201110, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GLI1.


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