Home Antibody All anti-GLDC antibodies
Also for GLDC (NM_000170)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 442 and 693 of Human GLDC|
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens glycine dehydrogenase (decarboxylating) (GLDC)|
|GCE; GCSP; HYGN1|
Entrez Gene 2731 Human
|The enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 220.127.116.11), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM]|
|Druggable Genome Glycine, serine and threonine metabolismMetabolic pathways|
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Sample (30 ug of whole cell lysate) A: Hela (anti-GLDC antibodydiluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Glycine dehydrogenase(anti-GLDC antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using Glycine dehydrogenase(anti-GLDC antibody) antibody at 1:200 dilution.