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Home Antibody All anti-GJA1 antibodies

Anti-GJA1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305614 Goat Anti-Connexin 43 / GJA1 Antibody 100ug $325 3-7 Days
LC400061 GJA1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-QPFDFPDDNQNSKK, from the internal region of the protein sequence according to NP_000156.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Rat. Expected from seq similarity: Human, Rat, Dog, Pig Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.3-1ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens gap junction protein, alpha 1, 43kDa (GJA1)
Alternative NameAVSD3; CMDR; CX43; GJAL; HLHS1; HSS; ODDD
Database LinkNP_000156
Entrez Gene 2697 Human
Entrez Gene 24392 Rat
Entrez Gene 403418 Dog
FunctionThis gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations. [provided by RefSeq].
Related PathwayIon Channels: OtherTransmembraneDruggable Genome Gap junctionArrhythmogenic right ventricular cardiomyopathy (ARVC)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA305614 (0.3ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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