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Home Antibody All anti-GFPT1 antibodies

Anti-GFPT1 Antibody EPR4854

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310529
  • Rabbit Monoclonal antibody against GFAT1
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for GFPT1 (NM_002056)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GFAT1 was used as an immunogen.
Clone NameEPR4854 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 79 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or ICC.

Reference Data

Target NameHomo sapiens glutamine--fructose-6-phosphate transaminase 1 (GFPT1), transcript variant 2
Alternative NameCMSTA1; GFA; GFAT; GFAT 1; GFAT1; GFAT1m; GFPT; GFPT1L; MSLG
Database LinkNP_002047
Entrez Gene 2673 Human
Entrez Gene 14583 Mouse
Entrez Gene 297417 Rat
FunctionGFAT1 is the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. It catalyzes the formation of glucosamine 6-phosphate (1). The GFAT-mediated amino sugar pathway has been shown to be involved in the desensitization of adipocytes to insulin by glucose in non-insulin-dependent diabetes mellitus (2). It is most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins (3).
Related PathwayProtease Alanine, aspartate and glutamate metabolismAmino sugar and nucleotide sugar metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-GFPT1 antibody [EPR4854]; All lanes : Anti-GFPT1 antibody [EPR4854] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : JAR cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Human placenta lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 79 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFPT1 antibody [EPR4854]; TA310529, at a 1/100 dilution, staining GFPT1 in paraffin-embedded Human testis tissue by immunohistochemistry.
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