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Home Antibody All anti-GCOM1 antibodies

Anti-GCOM1 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA320110 Rabbit Polyclonal MYOZAP Antibody 100ug $325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenMYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferMYOZAP Antibody is supplied in PBS containing 0.02% sodium azide.
Purification MYOZAP Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens GRINL1A combined protein (Gcom1), transcript variant 6
Alternative NameGup1, Gup2, Gcom2, GRINL1A, FLJ30973, MGC126694, MGC138353
Database LinkNP_001018105
Entrez Gene 145781 Human
FunctionMYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of MYOZAP in rat kidney tissue lysate with MYOZAP antibody at (A) 1 and (B) 2 ug/mL.
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Immunohistochemistry of MYOZAP in human lung tissue with MYOZAP antibody at 5 ug/mL.
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Immunofluorescence of MYOZAP in human lung tissue with MYOZAP antibody at 20 ug/mL.
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