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Home Antibody All anti-GCG antibodies

Anti-GCG Antibody EPR4042

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307489
  • Rabbit monoclonal antibody against GLP-1 (active)(clone EPR4042)
100ul 325 3-7 Days
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IHC(1)
ELISA(2)
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Also for GCG (NM_002054)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenGLP-1 (7-36, amide) conjugated to KLH was used as an immunogen. This antibody recognizes GLP-1 (active).
Clone NameEPR4042 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *ELISA, IHC Suggested DilutionsELISA: Use a concentration of 1 ug/ml; IHC-P: 1:100 - 1:250
Predicted MW Explanation 4 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ,IP or WB.

Reference Data

Target NameHomo sapiens glucagon (GCG)
Alternative NameGLP1; GLP2; GRPP
Database LinkNP_002045
Entrez Gene 2641 Human
FunctionGlucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2. GLP-1 stimulates glucose-dependent insulin secretion and insulin biosynthesis, inhibits glucagon secretion and gastric emptying, and inhibits food intake. The majority of circulating biologically active GLP-1 is found in GLP-1 (7-36, amide), with lesser amounts of bioactive GLP-1 (7-37) form also detectable (1). GLP-1 is inactivated by N-terminal degradation of the peptide by Dipeptidyl Peptidase-4 (DPP-4)-mediated cleavage at position 2, alanine. Application: ELISA and IHC. Optimal dilutions/concentrations should be determined by the end user.
Related PathwaySecreted ProteinES Cell Differentiation/IPSDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA Image
ELISA - Anti-GLP1 antibody [EPR4042]; ELISA: Glucagon-like Peptide (GLP-1) with various concentrations was coated into 96-wells. 1 ug/ml of anti-Glucagon-Like Peptide 1 (GLP-1, 7-36,amide) rabbit monoclonal antibody or the antibody from Vendor X was added. HRP conjugated goat anti-rabbit IgG antibody was used to develop the color.
ELISA Image
ELISA - Anti-GLP1 antibody [EPR4042]; ELISA: 1 ug/ml of GLP-1 was coated into 96-wells. Anti-Glucagon-Like Peptide 1 (GLP-1) rabbit monoclonal antibody or the antibody from Vendor X with various concentrations was added. HRP conjugated goat anti-rabbit IgG antibody was used to develop the color.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GLP1 antibody [EPR4042]; TA307489 at 1/100 dilution staining GLP1 in paraffin- embedded Human Pancreas tissue by Immunohistochemistry.

 

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