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Home Antibody All anti-GCG antibodies

Anti-GCG Antibody EPR4042

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307487
  • Rabbit monoclonal antibody against Glucagon-like peptide 1 (GLP-1)(clone EPR4042)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419562) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
ELISA(1)
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Also for GCG (NM_002054)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Glucagon-like peptide 1 (GLP-1) was used as an immunogen.
Clone NameEPR4042 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ELISA, IHC Suggested DilutionsELISA: Use a concentration of 1 ug/ml; WB: 1:200; IHC-P: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens glucagon (GCG)
Alternative NameGLP1; GLP2; GRPP
Database LinkNP_002045
FunctionGlucagon-like peptide 1 (GLP-1) is a gut hormone resulting from the proteolytic processing of preproglucagon (1). As a potent stimulator of glucose-dependent insulin release, it plays important roles in gastric motility and the suppression of plasma glucagon levels (2). GLP-1 increases islet mass through the stimulation of islet neogenesis and pancreatic beta cell proliferation (2). It also inhibits beta cell apoptosis (2). GLP-1 is secreted from intestinal L cells throughout the gastrointestinal tract and induced in response to nutrient ingestion (2). These physiological functions make GLP-1 a therapeutic target for type 2 diabetes, especially in the treatment of severe hypoglycemia in insulin-dependent diabetics (2).
Related Pathway
Signaling by GPCR

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WB Image
Western blot - Anti-Glicentin antibody [EPR4042]; Anti-Glicentin antibody [EPR4042] at 1/200 dilution + Glicentin polypeptide at 0.005 µg.Predicted band size : 21 kDa.
ELISA Image
ELISA - Anti-Glicentin antibody [EPR4042]; 1 ug/mL of Glucagon-like Peptide (GLP-1) was coated into 96-wells. Various concentrations of anti-Glucagon-Like Peptide 1 (GLP-1, 7-36,amide) rabbit monoclonal antibody was added. HRP conjugated goat anti-rabbit IgG antibody was used to develop the color.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Glicentin antibody [EPR4042]; TA307487, at 1/100 dilution, staining Glicentin in Human pancreas tissue by immunohistochemistry

 

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