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Anti-GBA TRUEMAB Antibody clone OTI1D12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA803361 GBA mouse monoclonal antibody, clone OTI1D12 100ul 325
In Stock
LC400055 GBA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF803361 Carrier-free (BSA/glycerol-free) GBA mouse monoclonal antibody, clone OTI1D12 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.
Clone Nameclone OTI1D12 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 55.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens glucosidase, beta, acid (GBA), transcript variant 1
Alternative NameGBA1; GCB; GLUC
Database LinkNP_000148
Entrez Gene 2629 Human
FunctionThis gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].
Related PathwayDruggable Genome Other glycan degradationSphingolipid metabolismMetabolic pathwaysLysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GBA (RC216061, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GBA.

IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-GBA mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA803361)


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