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Home Antibody All anti-GBA antibodies

Anti-GBA Antibody EPR5142

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310520
  • Rabbit Monoclonal antibody against Glucosylceramidase (GBA)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400055) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for GBA (NM_000157)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Glucosylceramidase was used as an immunogen.
Clone NameEPR5142 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens glucosidase, beta, acid (GBA), transcript variant 1
Alternative NameGBA1; GCB; GLUC
Database LinkNP_000148
Entrez Gene 2629 Human
FunctionGlucosylceramidase is a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in Glucosylceramidase cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides (1).
Related PathwayDruggable Genome Other glycan degradationSphingolipid metabolismMetabolic pathwaysLysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-GBA antibody [EPR5142]; All lanes : Anti-GBA antibody [EPR5142] at 1/1000 dilution.Lane 1 : Saos-2 cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 60 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GBA antibody [EPR5142]; TA310520, at a 1/50 dilution, staining GBA in paraffin-embedded Human colon tissue by immunohistochemistry.

 

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