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Anti-GBA Antibody EPR5142


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA310520 Rabbit Monoclonal antibody against Glucosylceramidase (GBA) 100ul $325 In Stock
LC400055 GBA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Glucosylceramidase was used as an immunogen.
Clone NameEPR5142 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens glucosidase, beta, acid (GBA), transcript variant 1
Alternative NameGBA1; GCB; GLUC
Database LinkNP_000148
Entrez Gene 2629 Human
FunctionGlucosylceramidase is a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in Glucosylceramidase cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides (1).
Related PathwayDruggable Genome Other glycan degradationSphingolipid metabolismMetabolic pathwaysLysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-GBA antibody [EPR5142]; All lanes : Anti-GBA antibody [EPR5142] at 1/1000 dilution.Lane 1 : Saos-2 cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 60 kDa.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GBA antibody [EPR5142]; TA310520, at a 1/50 dilution, staining GBA in paraffin-embedded Human colon tissue by immunohistochemistry.


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