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Anti-GATM TRUEMAB Antibody clone 1C9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA503147
  • GATM mouse monoclonal antibody,clone 1C9
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419923) , 20ug Explanation
100ul
30ul
$325 In Stock
CF503147
  • Carrier-free (BSA/glycerol-free) GATM mouse monoclonal antibody,clone 1C9
100ug $450 3-4 weeks
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WB(2)
IHC(4)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human GATM(NP_001473) produced in HEK293 cell.
Clone Nameclone 1C9 IsotypeIgG1
Species ReactivityHuman Concentration0.41 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 44.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens glycine amidinotransferase (L-arginine:glycine amidinotransferase) (GATM)
Alternative NameAGAT; AT; CCDS3
Database LinkNP_001473
Entrez Gene 2628 Human
FunctionThis gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq].
Related PathwayDruggable Genome Glycine, serine and threonine metabolismArginine and proline metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GATM (RC200474, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GATM.
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Western blot analysis of extracts (10ug) from 9 Human tissue by using anti-GATM monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon).
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-GATM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503147)
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Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-GATM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503147)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-GATM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503147)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-GATM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503147)
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Anti-GATM mouse monoclonal antibody (TA503147) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GATM(RC200474).
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HEK293T cells transfected with either RC200474 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-GATM antibody(TA503147), and then analyzed by flow cytometry.
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