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Anti-GAS2 Antibody EPR1742(2)
Also for GAS2 (NM_177553)
|A synthetic peptide corresponding to residues on the N-terminus in human Gas-2 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100
|Does not react with Rat. Is unsuitable for Flow Cyt or ICC.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or ICC.
|Homo sapiens growth arrest-specific 2 (GAS2), transcript variant 2|
|Gas-2 (Growth arrest-specific protein 2) is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis (1). It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity (1). Gas-2 is cleaved during apoptosis, and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells (2).|
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Western blot - GAS2 antibody [EPR1742(2)]; All lanes : Anti-GAS2 antibody [EPR1742(2)] at 1/1000 dilution.Lane 1 : HepG2 lysate.Lane 2 : Human fetal liver lysate.Lane 3 : Human fetal kidney lysate.Lane 4 : Jurkat lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 35 kDa.Observed band size : 35 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GAS2 antibody [EPR1742(2)]; Immunohistochemical analysis of paraffin-embedded Human stomach tissue using ab109762 at a dilution of 1/50.