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Home Antibody All anti-GALR2 antibodies

Anti-GALR2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308347
  • Rabbit Polyclonal antibody to Galanin Receptor 2 (galanin receptor 2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401272) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 212 and 277 of Human GALR2
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens galanin receptor 2 (GALR2)
Alternative NameGAL2-R; GALNR2; GALR-2
Database LinkNP_003848
FunctionGalanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq]
Related Pathway
Signaling by GPCR

* Availability is in business days
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WB Image
Sample(30 ug whole cell lysate) A:293T B:H1299 (anti-GALR2 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded Skin, using Galanin Receptor 2(anti-GALR2 antibody) antibody(10 ?g/ml).

 

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