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Home Antibody All anti-GADD45B antibodies

Anti-GADD45B Antibody EPR1235(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310513
  • Rabbit Monoclonal antibody against GADD45 beta (GADD45B)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC414404) , 20ug
100ul $325 In Stock
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WB(1)
Assay(1)
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Also for GADD45B (NM_015675)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GADD45 beta was used as an immunogen.
Clone NameEPR1235(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens growth arrest and DNA-damage-inducible, beta (GADD45B)
Alternative NameGADD45BETA; MYD118
Database LinkNP_056490
FunctionGADD45 beta is a member of a group of proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The proteins in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of their protein products is involved in the regulation of growth and apoptosis. These proteins are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth (1).
Related Pathway
Adipogenesis
Cell cycle
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-GADD45B antibody [EPR1235(2)]; All lanes : Anti-GADD45B antibody [EPR1235(2)] at 1/10000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : Fetal liver cell lysate.Lane 3 : Fetal heart cell lysate.Lane 4 : A549 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 18 kDa.
Assay Image
Other-Anti-GADD45B antibody [EPR1235(2)](TA310513); Equilibrium disassociation constant (KD)..

 

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