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Anti-GAB2 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA312746 Rabbit polyclonal Gab2 (Ser623) antibody(Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Gab2 around the phosphorylation site of serine 623 (PS-SP-P-S).
Clone Name IsotypeIgG
Species ReactivityHuman (Identities = 100%, Positives = 100%); Mouse (Identities = 91%, Positives = 91%);Rat (Identities = 91%, Positives = 91%) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:1000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note Gab2 (Phospho-Ser623) antibody detects endogenous levels of Gab2 only when phosphorylated at serine 623.

Reference Data

Target NameHomo sapiens GRB2-associated binding protein 2 (GAB2), transcript variant 2
Alternative NameKIAA0571
Database LinkNP_036428
Entrez Gene 9846 Human
Entrez Gene 14389 Mouse
Entrez Gene 84477 Rat
Related PathwayDruggable Genome Fc epsilon RI signaling pathwayFc gamma R-mediated phagocytosisChronic myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 30mins), using Gab2 (Phospho-Ser623) antibody.The lane on the right is treated with the synthesized peptide.

WB Image
Western blot analysis of extracts from 293 cells (Lane 2), HeLa cells (Lane 3) and HepG2 cells (Lane 4), using Gab2 (Phospho-Ser623) Antibody. The lane on the left is treated with synthesized peptide.

IHC Image
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Gab2 (Phospho-Ser623) antibody.The picture on the right is treated with the synthesized peptide.


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