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Anti-GAB2 PHOSPHO Antibody

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SKU Description Amount Price Availability*  
TA312745
  • Rabbit polyclonal Gab2 (Tyr643) antibody(Phospho-specific)
100ul $325 In Stock
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WB(2)
IHC(1)

OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Gab2 around the phosphorylation site of tyrosine 643 (V-D-YP-V-Q).
Clone Name IsotypeIgG
Species ReactivityHuman (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%);Rat (Identities = 100%, Positives = 100%) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:40000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note Gab2 (Phospho-Tyr643) antibody detects endogenous levels of Gab2 only when phosphorylated at tyrosine 643.

Reference Data

Target NameHomo sapiens GRB2-associated binding protein 2 (GAB2), transcript variant 2
Alternative NameKIAA0571
Database LinkNP_036428
Entrez Gene 9846 Human
Entrez Gene 14389 Mouse
Entrez Gene 84477 Rat
Function
Related PathwayDruggable Genome Fc epsilon RI signaling pathwayFc gamma R-mediated phagocytosisChronic myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts from Jurkat cells, treated with IFN (2500U/ML, 30mins), using Gab2 (Phospho-Tyr643) antibody.The lane on the right is treated with the synthesized peptide.
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Western blot analysis of extracts from 3T3 cells (Lane 2), using Gab2 (Phospho-Tyr643) Antibody. The lane on the left is treated with synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using Gab2 (Phospho-Tyr643) antibody.The picture on the right is treated with the synthesized peptide.
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