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Anti-Fos Antibody EPR883(2)
|A synthetic peptide corresponding to residues in human Fos was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens FBJ murine osteosarcoma viral oncogene homolog (FOS)|
|AP-1; C-FOS; p55|
|Fos is nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, Fos and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (1). In some cases, expression of the FOS protein has also been associated with apoptotic cell death (2).|
EGFR1 Signaling Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
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Western blot - Anti-c-Fos antibody [EPR883(2)]; All lanes : Anti-c-Fos antibody [EPR883(2)] at 1/1000 dilution.Lane 1 : Lysate of U937 cells treated with TPA.Lane 2 : U937 cell lysate.Lane 3 : Lysate of HeLa cells treated with TPA.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat ant-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 62 kDa .