Home Antibody All anti-Fcn1 antibodies
Also for Fcn1 (NM_002003)
|Synthetic peptide surrounding amino acid 320 of rat Ficolin-1 |
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens ficolin (collagen/fibrinogen domain containing) 1 (FCN1)|
Entrez Gene 2219 Human
|Ficolin-1 also known as M-Ficolin is a pattern recognition molecule of the lectin complement activation pathway. It is expressed mostly in monocytes, nuetrophils and in type II alveolar epithelial cells. Ficolin-1 is detected on the surface of circulating monocytes but is not present in the plasma. Ficolin-1 has a 28 aa signal sequence, an N-terminal collagen domain and a C-terminal fibrinogen-like (FBG) domain that contain a calcium binding site and a potential N-glycosylation site.|
|Secreted ProteinDruggable Genome |
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Western blot analysis of Ficolin-1 in 3T3 cell lysate (Lane 1) and rat kidney tissue lysate (Lane 4).