FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit (1). FXR1 regulates intracellular transport and local translation of certain mRNAs. It is also required for embryonic and postnatal development of muscle tissue (2).
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