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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-FXN antibodies

Anti-FXN TrueMAB Antibody Clone 3C3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA504352
  • Purified FXN (Frataxin) mouse monoclonal antibody, Clone 3C3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400054) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF504352
  • Carrier-free (BSA/glycerol-free) FXN mouse monoclonal antibody,clone 3C3
100ug $450 3-4 weeks Add to Shopping Cart
WB(1)
IF(1)
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Also for FXN (NM_000144)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1
Synonyms:CyaY; FA; FARR; FRDA; X25
ImmunogenFull length human recombinant protein of human FXN(NP_000135) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 3C3 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IF Suggested DilutionsWB 1:2000, IF 1:100,
BackgroundThis nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FXN (RC204880, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FXN.
IF Image
Anti-FXN mouse monoclonal antibody (TA504352) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FXN(RC204880).

 

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