Home Antibody All anti-FXN antibodies
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FXN.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1: 100~500; IHC: 1: 10~50; ELISA: 1: 1,000;
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
|Homo sapiens frataxin (FXN), transcript variant 1|
|CyaY; FA; FARR; FRDA; X25|
|FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.|
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(LEFT)Western blot analysis of FXN (arrow) using rabbit polyclonal FXN Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FXN gene (Lane 2) (Origene Technologies). (RIGHT)Western blot analysis of anti-FXN Antibody (C-term) in 293 cell line lysates (35ug/lane). FXN (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FXN antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.