Home Antibody All anti-FXN antibodies
|This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the C-terminal region of human FXN.|
|Human (Predicted: Mouse)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000, IHC: 1:10~50
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|Homo sapiens frataxin (FXN), transcript variant 1|
|CyaY; FA; FARR; FRDA; X25|
Entrez Gene 2395 Human
Entrez Gene 14297 Mouse
|FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.|
|Druggable Genome |
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Western blot analysis of anti-FXN Antibody (C-term) (Cat#TA302102) in 293 cell line lysates (35ug/lane). FXN (arrow) was detected using the purified Pab.
Western blot analysis of FXN (arrow) using rabbit polyclonal FXN Antibody (C-term) (RB12571). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FXN gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FXN antibody (C-term) (Cat.#TA302102), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.