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Anti-FUS Antibody EPR5812
Also for FUS (NM_001010850)
|A synthetic peptide corresponding to residues in human FUS was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:10 - 1:100; ICC/IF: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for IP.
|Homo sapiens fusion (involved in t(12;16) in malignant liposarcoma) (FUS), transcript variant 2|
|TLS, FUS1, FUS-CHOP|
|FUS is a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. FUS belongs to the FET family of RNA-binding proteins, which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Defects in FUS result in amyotrophic lateral sclerosis type 6 (1). |
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Western blot - Anti-TLS/FUS antibody [EPR5812]; All lanes : Anti-TLS/FUS antibody [EPR5812] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : Human fetal brain lysate.Lane 3 : Caco 2 cell lysate.Lane 4 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 53 kDa.Observed band size : 73 kDa .
Other-Anti-TLS/FUS antibody [EPR5812](ab124923); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TLS/FUS antibody [EPR5812]; ab124923, at 1/50 dilution, staining TLS/FUS in formalin-fixed, paraffin-embedded Human kidney tissue, by Immunohistochemistry.