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Anti-FREM2 Antibody Polyclonal
Also for FREM2 (NM_207361)
|FREM2 antibody was raised against a 19 amino acid synthetic peptide near the center of human FREM2.|
||ELISA, WB, ICC: 20 ug/ml, IF: 20 ug/ml
|FREM2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|FREM2 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens FRAS1 related extracellular matrix protein 2 (FREM2)|
|DKFZp686J0811; DKFZp781I048; KIAA1074|
|FREM2 Antibody: FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.|
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Western blot analysis of FREM2 in A-20 cell lysate with FREM2 antibody at (A) 0.5 and (B) 1ug/mL.
Immunocytochemistry of FREM2 in A-20 cells with FREM2 antibody at 20 ug/mL.