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Home Antibody All anti-FOXP3 antibodies

Anti-FOXP3 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319911 Rabbit Polyclonal FOXP3 Antibody 100ug $325 2 Weeks
LC402270 FOXP3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for FOXP3 (NM_001114377)
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OriGene Data

ImmunogenRabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation 47 kDa
BufferFOXP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification FOXP3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens forkhead box P3 (FOXP3), transcript variant 2
Database LinkNP_001107849
Entrez Gene 50943 Human
Entrez Gene 20371 Mouse
Entrez Gene 317382 Rat
FunctionFOXP3 Antibody: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FOXP3 in A549 cell lysate with FOXP3 antibody at (A) 1 and (B) 2 ug/mL.


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