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Home Antibody All anti-FOXO4 antibodies

Anti-FOXO4 Antibody EPR2150(3)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310501
  • Rabbit Monoclonal antibody against FOXO4
100ul $325 3-7 Days
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WB(1)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human FOXO4 was used as an immunogen.
Clone NameEPR2150(3) IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens forkhead box O4 (FOXO4), transcript variant 2
Alternative NameAFX; AFX1; MLLT7
Database LinkNP_001164402
Entrez Gene 4303 Human
FunctionFOXO4 is a member of the O class of winged helix/forkhead transcription factor family. It is regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this protein on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia (1). A constitutively active FOXO4 mutant where phosphorylation sites Thr-32, Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival, transformation and tumorigenicity (2).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-FOXO4 antibody [EPR2150(3)]; All lanes : Anti-FOXO4 antibody [EPR2150(3)] at 1/10000 dilution.Lane 1 : HA-FOXO4 transfected 293T cell lysate.Lane 2 : HA-FOXO4.A3 (T32, S197 and S262 mutated to A) transfected 293T cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP-conjugated goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.
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Other-Anti-FOXO4 antibody [EPR2150(3)](TA310501); Equilibrium disassociation constant (KD)..
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXO4 antibody [EPR2150(3)]; TA310501, at 1/100 dilution, staining FOXO4 in paraffin-embedded Human placenta tissue by Immunohistochemistry.
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