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Home Antibody All anti-Fos antibodies

Anti-Fos Antibody EPR883(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310495
  • Rabbit Monoclonal antibody against Fos
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401614) , 20ug
100ul 325 In Stock
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WB(1)
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Also for Fos (NM_005252)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Fos was used as an immunogen.
Clone NameEPR883(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:10 - 1:100
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens FBJ murine osteosarcoma viral oncogene homolog (FOS)
Alternative NameAP-1; C-FOS; p55
Database LinkNP_005243
FunctionFos is nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, Fos and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (1). In some cases, expression of the FOS protein has also been associated with apoptotic cell death (2).
Related Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-c-Fos antibody [EPR883(2)]; All lanes : Anti-c-Fos antibody [EPR883(2)] at 1/1000 dilution.Lane 1 : Lysate of U937 cells treated with TPA.Lane 2 : U937 cell lysate.Lane 3 : Lysate of HeLa cells treated with TPA.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat ant-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 62 kDa .

 

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