Anti-Fos Antibody, EPR883(2)

Also for Fos (NM_005252)

Gene Name	Homo sapiens FBJ murine osteosarcoma viral oncogene homolog (FOS)
Synonyms:	AP-1; C-FOS; p55
Immunogen	A synthetic peptide corresponding to residues in human Fos was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR883(2)	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000-10,000; IHC 1:250 - 500; ICC: 1:100 - 250; IP: 1:10 - 100; FC: 1:10 - 100;
Background	Fos is nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, Fos and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (1). In some cases, expression of the FOS protein has also been associated with apoptotic cell death (2).
Related Pathway	EGFR1 Signaling Pathway MAPK signaling pathway TGF Beta Signaling Pathway Toll-like receptor signaling pathway

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WB Image

Western blot analysis on (A) U937 treated with TPA, (B) U937, (C) HeLa treated with TPA, and (D) HeLa cell lysates using anti-Fos RabMAb.

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Anti-Fos Antibody EPR883(2)

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