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Home Antibody All anti-FOLH1 antibodies

Anti-FOLH1 TRUEMAB Antibody Clone OTI9E6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504567 FOLH1 mouse monoclonal antibody, clone OTI9E6 (formerly 9E6) 100ul $325 In Stock
LC417950 FOLH1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504567 Carrier-free (BSA/glycerol-free) FOLH1 mouse monoclonal antibody, clone OTI9E6 (formerly 9E6) 100ug $450 3-4 weeks
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WB(1)
ELISA(1)
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Also for FOLH1 (NM_004476)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.
Clone NameClone OTI9E6 IsotypeIgG1
Species ReactivityHuman Concentration0.65 mg/ml
Guaranteed Application *WB, ELISA Suggested DilutionsWB 1:2000,
Predicted MW Explanation 84.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1
Alternative NameFGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
Database LinkNP_004467
Entrez Gene 2346 Human
FunctionThis gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq].
Related PathwayTransmembraneProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOLH1 (RC218310, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOLH1.
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Standard curve for ELISA analysis with FOLH1 recombinant protein (dilution range from 5ng/ml to 5µg/ml) using FOLH1 Capture Antibody (Cat# TA504567) at 5µg/ml and HRP conjugated FOLH1 Detection mAb (Cat# TA504550) at 0.03µg/ml.
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