Home Antibody All anti-FOLH1 antibodies
Anti-FOLH1 TRUEMAB Antibody Clone OTI2E1
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for FOLH1 (NM_004476)
|Full length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.|
|Human , Dog , Rat , Monkey , Mouse
|WB, ELISA, IF
||WB 1:500~2000, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1|
|FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA|
Entrez Gene 2346 Human
Entrez Gene 53320 Mouse
Entrez Gene 85309 Rat
Entrez Gene 707714 Monkey
Entrez Gene 476775 Dog
|This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq]. |
|TransmembraneProteaseDruggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FOLH1 (RC218310, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FOLH1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-FOLH1 monoclonal antibody.
Western blot analysis of extracts (10ug) from 9 Human tissue by using anti-FOLH1 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: Colon).
Standard curve for ELISA analysis with FOLH1 recombinant protein (dilution range from 5ng/ml to 5µg/ml) using FOLH1 Capture Antibody (Cat# TA504509) at 5µg/ml and HRP conjugated FOLH1 Detection mAb (Cat# TA504550) at 0.03µg/ml.
Anti-FOLH1 mouse monoclonal antibody (TA504509) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FOLH1(RC218310).