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Anti-FNTB Antibody EPR4706
Also for FNTB (NM_002028)
|A synthetic peptide corresponding to residues near the N-terminus of human FNTB was used as an immunogen.|
||Tissue culture supernatant
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; ICC: 1:50 - 1:100
|Does not react with Mouse. Is unsuitable for Flow Cyt,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens farnesyltransferase, CAAX box, beta (FNTB)|
|The mammalian enzyme protein farnesyltransferase is a heterodimeric protein composing of two nonidentical subunits designated alpha and beta, which catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins (1,2). The beta subunit is responsible for peptide-binding (1). Chemical modification and site-directed mutagenesis studies have identified a conserved cysteine residue of protein farnesyltransferase, Cys299, in the beta subunit, as important for catalytic activity and zinc binding, suggesting that the thiolate of this residue may directly coordinate the zinc ion (3).|
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Western blot - FNTB antibody [EPR4706]; All lanes : Anti-FNTB antibody [EPR4706] at 1/1000 dilution.Lane 1 : JAR cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : K562 cell lysate.Lane 4 : SH-SY5Y cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 49 kDa.