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Home Antibody All anti-FNIP2 antibodies

Anti-FNIP2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306734
  • Rabbit Polyclonal FNIP2 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC412262) , 20ug
100ug $325 In Stock
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WB(1)
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Also for FNIP2 (NM_020840)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFNIP2 antibody was raised against an 18 amino acid peptide near the amino terminus of human FNIP2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens folliculin interacting protein 2 (FNIP2)
Alternative NameFNIPL; MAPO1
Database LinkNP_065891
FunctionFNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49% identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship. Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
Related Pathway

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WB Image
Western blot analysis of FNIP2 in mouse skeletal muscle lysate with FNIP2 antibody at (A) 1 and (B) 2 µg/ml.

 

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