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Anti-FN1 TRUEMAB Antibody Clone OTI1G2
TrueMAB Antibodies - Made against Authentic Protein Antigens
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|Human recombinant protein fragment corresponding to amino acids 32-307 of human FN1 (NP_473375) produced in E.coli.|
||WB 1:500, IHC 1:150,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens fibronectin 1 (FN1), transcript variant 7|
|CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF|
Entrez Gene 2335 Human
|This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].|
|Secreted ProteinES Cell Differentiation/IPSDruggable Genome Focal adhesionECM-receptor interactionRegulation of actin cytoskeletonPathways in cancerSmall cell lung cancer|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FN1 (RC212860, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FN1.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-FN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803733)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803733)