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Home Antibody All anti-FMR1 antibodies

Anti-FMR1 TRUEMAB Antibody Clone OTI5B9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504373 FMR1 (FMRP ) mouse monoclonal antibody, clone OTI5B9 (formerly 5B9) 100ul $325 In Stock
LC419580 FMR1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504373 Carrier-free (BSA/glycerol-free) FMR1 mouse monoclonal antibody, clone OTI5B9 (formerly 5B9) 100ug $450 3-4 weeks
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WB(2)
IHC(10)
IF(1)
FC(2)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.
Clone NameClone OTI5B9 IsotypeIgG1
Species ReactivityHuman Concentration3.08 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 71 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1
Alternative NameFMRP; FRAXA; POF; POF1; POFX
Database LinkNP_002015
Entrez Gene 2332 Human
FunctionThe protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (RC222699, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.
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Western blot analysis of extracts (10ug) from 1 cell line by using anti-FMR1 monoclonal antibody.(1:200)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-FMR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504373)
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Anti-FMR1 mouse monoclonal antibody (TA504373) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1(RC222699).
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Flow cytometric Analysis of Hela cells, using anti-FMR1 antibody(TA504373),(Red), compared to a nonspecific negative control antibody,(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-FMR1 antibody(TA504373),(Red), compared to a nonspecific negative control antibody,(Blue).
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