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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-FMR1 antibodies

Anti-FMR1 TrueMAB Antibody clone 1C6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA504290
  • Purified FMR1 (FMRP ) mouse monoclonal antibody, clone 1C6
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419580) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF504290
  • Carrier-free (BSA/glycerol-free) FMR1 mouse monoclonal antibody,clone 1C6
100ug $450 8-10 Days Add to Shopping Cart
WB(2)
IHC(12)
IF(1)
FC(1)
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Also for FMR1 (NM_002024)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1
Synonyms:FMRP; FRAXA; POF; POF1; POFX
ImmunogenHuman recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 1C6 IsotypeIgG1
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF, FC Suggested Dilutions WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
BackgroundThe protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FMR1 (RC222699, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FMR1.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-FMR1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FMR1 mouse monoclonal antibody. (TA504290)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-FMR1 mouse monoclonal antibody. (TA504290)
IF Image
Anti-FMR1 mouse monoclonal antibody (TA504290) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FMR1(RC222699).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-FMR1 antibody(TA504290),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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