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Home Antibody All anti-FMO1 antibodies

Anti-FMO1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308880 Rabbit polyclonal antibody to FMO1 (flavin containing monooxygenase 1) 100ul $325 3-7 Days
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 437 of FMO1 (Uniprot ID#Q01740)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Dog, Pig, Rat, Bovine) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 60kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (83%), Dog (88%), Pig (86%), Rat (82%), Bovine (85%)

Reference Data

Target NameHomo sapiens flavin containing monooxygenase 1 (FMO1), transcript variant 2
Alternative NameFlavin-containing monooxygenase 1 (fetal liver); OTTHUMP00000033536; OTTHUMP00000033537; flavin containing monooxygenase 1
Database LinkNP_002012
Entrez Gene 2326 Human
Entrez Gene 14261 Mouse
Entrez Gene 25256 Rat
Entrez Gene 403604 Dog
FunctionMetabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq]
Related PathwayDruggable Genome Drug metabolism - cytochrome P450

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate). A:Hep G2 . B:Raji . 7.5% SDS PAGE. TA308880 diluted at 1:1000


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