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Anti-FLOT1 Antibody EP446Y


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal Antibody against FLOT1 (Clone EP446Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401763) , 20ug Explanation
100ul $325 3-7 Days
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Also for FLOT1 (NM_005803)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Flotillin-1 was used as immunogen.
Clone NameEP446Y IsotypeIgG
Species ReactivityMouse, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500 - 1:1000
Predicted MW Explanation 48 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens flotillin 1 (FLOT1)
Alternative NameOTTHUMP00000029208; integral membrane component of caveolae; flotillin 1
Database LinkNP_005794
Entrez Gene 10211 Human
Entrez Gene 14251 Mouse
FunctionFlotillin-1, also known as Reggie-2, belongs to a larger family of proteins that share an evolutionarily conserved stomatin/prohibitin/flotillin/HflK/C (SPFH) domain (1). Flotillin-1 is a lipid raft-associated protein that has been implicated in various cellular processes. Flotillin was first found in cells that lack morphologically definable caveolae, as well as in non-caveolar membranes (2) and was subsequently identified in low density detergent-insoluble complexes of endothelial cells, where they were termed flotillins (3). As well as its postulated role in neuronal regeneration, flotilllin-1 has been implicated in insulin signaling to trigger glucose transporter redistribution in adipocytes (4) Flotillin also associates with phagosomes in macrophages (5).
Related Pathway Insulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Flotillin 1 antibody [EP446Y]; Anti-Flotillin 1 antibody [EP446Y] at 1/500 dilution + K562 cell lysate .Predicted band size : 48 kDa.Observed band size : 48 kDa.


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