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Anti-FLAP Antibody EPR5640
Also for FLAP (NM_001629)
|A synthetic peptide corresponding to residues in human FLAP was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
|Homo sapiens arachidonate 5-lipoxygenase-activating protein (ALOX5AP), transcript variant 1|
Entrez Gene 241 Human
|FLAP, along with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites that have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. It localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation (1). |
|TransmembraneDruggable Genome |
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Western blot - Anti-FLAP antibody [EPR5640]; All lanes : Anti-FLAP antibody [EPR5640] at 1/1000 dilution.Lane 1 : Raji cell lysates.Lane 2 : THP1 cell lysates.Lane 3 : HepG2 cell lysates.Lane 4 : K562 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 18 kDa.
Other-Anti-FLAP antibody [EPR5640](TA310491); Equilibrium disassociation constant (KD)..