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Anti-FKBP5 Antibody EPR6617
Also for FKBP5 (NM_001145775)
|A synthetic peptide corresponding to residues near the C-terminus of human FKBP5 was used as an immunogen.|
|Rat, Human (Does not react with: Mouse)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Does not react with Mouse
|Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 2|
|AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10|
Entrez Gene 2289 Human
Entrez Gene 361810 Rat
|FKBP5 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. FKBP5 also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This protein has been found to have multiple polyadenylation sites (1). |
|Druggable Genome |
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Western blot - Anti-FKBP51 antibody [EPR6617]; All lanes : Anti-FKBP51 antibody [EPR6617] at 1/1000 dilution.Lane 1 : Human testis cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : Caco-2 cell lysate.Lane 4 : HeLa cell lysate.Predicted band size : 51 kDa.
Other-Anti-FKBP51 antibody [EPR6617](TA310489); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FKBP51 antibody [EPR6617]; TA310489, at 1/50 dilution, stains FKBP51 in paraffin embedded human colon tissue by immunohistochemistry.