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Home Antibody All anti-FKBP1A antibodies

Anti-FKBP1A TRUEMAB Antibody clone 3B3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500557
  • FKBP1A (FKBP12) mouse monoclonal antibody, clone 3B3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400279) , 20ug
100ul 379 In Stock
CF500557
  • Carrier-free (BSA/glycerol-free) FKBP1A mouse monoclonal antibody, clone 3B3
100ug $450 3-4 weeks
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WB(1)
IHC(2)
FC(1)
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Also for FKBP1A (NM_000801)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human FKBP1A (NP_000792) produced in HEK293T cell.
Clone Nameclone 3B3 IsotypeIgG2b
Species ReactivityHuman Concentration0.80 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:2000, IHC 1:150, FLOW 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 1
Alternative NameFKBP-12; FKBP-1A; FKBP1; FKBP12; PKC12; PKCI2; PPIASE
Database LinkNP_000792
FunctionThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq].
Related Pathway
TGF Beta Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FKBP1A (RC201237, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FKBP1A.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-FKBP1A mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500557)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-FKBP1A mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500557)
FC Image
HEK293T cells transfected with either RC201237 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-FKBP1A antibody(TA500557), and then analyzed by flow cytometry.

 

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