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Anti-FGG TRUEMAB Antibody Clone OTI5C9
TrueMAB Antibodies - Made against Authentic Protein Antigens
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|Full length human recombinant protein of human FGG(NP_000500) produced in HEK293T cell.|
|Human , Dog , Rat , Monkey , Mouse
|| WB 1:400~4000, IHC 1:150,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens fibrinogen gamma chain (FGG), transcript variant gamma|
|fibrinogen, gamma chain; fibrinogen, gamma polypeptide; fibrinogen gamma chain|
Entrez Gene 2266 Human
Entrez Gene 99571 Mouse
Entrez Gene 24367 Rat
Entrez Gene 698363 Monkey
Entrez Gene 475474 Dog
|The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul |
|Secreted ProteinTransmembraneDruggable Genome Complement and coagulation cascades|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGG (RC202770, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGG.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-FGG monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-FGG mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507155)