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Home Antibody All anti-FGFRL1 antibodies

Anti-FGFRL1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308002
  • Rabbit polyclonal antibody to FGFR-5 (fibroblast growth factor receptor-like 1)
100ul 325 3-7 Days
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WB(2)
IHC(1)
IF(1)
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Also for FGFRL1 (NM_001004358)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 150 and 476 of FGFR5 (Uniprot ID#Q8N441)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 55kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (88%), Rat (89%)

Reference Data

Target NameHomo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 2
Alternative NameFGFR5; FHFR
Database LinkNP_001004358
Entrez Gene 53834 Human
Entrez Gene 116701 Mouse
Entrez Gene 360903 Rat
FunctionThe protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
FGFR-5 antibody detects FGFR-5 protein by Western blot analysis. A. 30 ug Jurkat whole cell lysate/extract. B. 30 ug Raji whole cell lysate/extract. C. 30 ug K562 whole cell lysate/extract. D. 30 ug NCI-H929 whole cell lysate/extract. 10 % SDS-PAGE. FGFR-
WB Image
FGFR-5 antibody detects FGFR-5 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. C. 30 ug HeLa whole cell lysate/extract. D. 30 ug HepG2 whole cell lysate/extract. 10 % SDS-PAGE. FGFR-5 ant
IHC Image
Immunohistochemical analysis of paraffin-embedded Oral CA Cal27 xenograft, using FGFRL1(TA308002) antibody at 1:100 dilution.
IF Image
FGFR-5 antibody detects FGFR-5 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: FGFR-5 protein stained by FGFR-5 antibody (TA308002) diluted at 1:500. Blue: Hoechst 33342 sta

 

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