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Home Antibody All anti-FGFRL1 antibodies

Anti-FGFRL1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308002
  • Rabbit polyclonal antibody to FGFR-5 (fibroblast growth factor receptor-like 1)
100ul 325 3-7 Days
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WB(1)
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Also for FGFRL1 (NM_001004358)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 150 and 486 of Human FGFRL1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 2
Alternative NameFGFR5; FHFR
Database LinkNP_001004358
FunctionThe protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]
Related Pathway

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WB Image
Sample(30 ug whole cell lysate) A:293T B:HepG2 C:Raji (anti-FGFRL1 antibody diluted at 1:1000)

 

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