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Home Antibody All anti-FGFR1 antibodies

Anti-FGFR1 TRUEMAB Antibody Clone 5D5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA803096
  • FGFR1 mouse monoclonal antibody,clone 5D5
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402963) , 20ug
100ul 325 In Stock
CF803096
  • Carrier-free (BSA/glycerol-free) FGFR1 mouse monoclonal antibody,clone 5D5
100ug $450 3-4 Days
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WB(1)
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Also for FGFR1 (NM_023110)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-376 of human FGFR1 (NP_075598)produced in SF9 cell.
Clone NameClone 5D5 IsotypeIgG1
Species ReactivityHuman Concentration1.00mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from cell culture supernatant by affinity chromatography

Reference Data

Target NameHomo sapiens fibroblast growth factor receptor 1 (FGFR1), transcript variant 1
Alternative NamebFGF-R-1; BFGFR; CD331; CEK; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD
Database LinkNP_075598
FunctionThe protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
Related Pathway
Adherens junction
MAPK signaling pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGFR1 (RC202080, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGFR1.</title><style>.apon{position:absolute;clip:rect(471px,auto,auto,471px);}</style><div class=apon>approval <a href=http://crazypaydayloansonline.com >payday loans</a></div>

 

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